Arş. Gör. DİDEM AKKAYA

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Makaleler 22

1. **Biological and Phytochemical Investigations of Alchemilla daghestanica Juz. and Alchemilla minusculiflora Buser: A Focus on Anti-Inflammatory and Skin-Regenerative Properties**

Ortahisar M., Cigsar T., SEYHAN G., AKKAYA D., Uzuner S., BARUT B., et al.

CHEMISTRY & BIODIVERSITY , cilt.22, sa.12, 2025 (SCI-Expanded, Scopus)

2. Synthesis, characterization, in vitro cholinesterase inhibition and cytotoxic activity of silicon(IV) phthalocyanines containing anthraquinone groups against lung and colorectal cancer cells

Keleş T., Bıyıklıoğlu Z., Ali Y. A., Akkaya D., Yalçın C. Ö., Barut B.

JOURNAL OF MOLECULAR STRUCTURE , cilt.1330, 2025 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

3. A comparative study evaluating the antioxidant activities of rosemary extracts and commercial products

Gökkaya İ., Akkaya D., Ersoy S., Barut B., Renda G.

ISTANBUL JOURNAL OF PHARMACY , cilt.55, sa.1, ss.192-199, 2025 (ESCI, TRDizin) Sürdürülebilir Kalkınma

4. Phytochemical Analysis and Assessment of Antioxidant and Enzyme Inhibitory Activity of Alchemilla pseudocartalinica Juz.

Uzunkaya Ç., Gökkaya İ., Akkaya D., Soral M., Seyhan G., Barut B., et al.

Chemistry & biodiversity , cilt.22, sa.2, 2025 (SCI-Expanded, Scopus)

5. Synthesis and cholinesterases inhibitory effects of water soluble zinc(II) and silicon(IV) phthalocyanines bearing ({8-[3-(dimethylamino)phenoxy]octyl}oxy) groups

Usta B., SEYHAN G., AKKAYA D., BARUT B., BIYIKLIOĞLU Z., ÖZEL A.

APPLIED ORGANOMETALLIC CHEMISTRY , cilt.38, sa.11, 2024 (SCI-Expanded, Scopus)

6. **Alpha-Glucosidase Inhibitory Effects of Flavonoids, Phenolic Acids and Iridoids Isolated From Vinca Soneri: In Vitro and In Silico Perspectives**

Uyanir E., Soral M., SEYHAN G., AKKAYA D., BARUT B., SARI S., et al.

CHEMISTRY & BIODIVERSITY , cilt.21, sa.10, 2024 (SCI-Expanded, Scopus)

7. Synthesis, characterization and biological activity potential of some novel thiourea derivatives

Türk S., Akkaya D., Kırılmaz B., Önal E. M., Barut B.

JOURNAL OF RESEARCH IN PHARMACY , cilt.28, sa.6, ss.1911-1920, 2024 (ESCI, TRDizin)

8. The synthesis and therapeutic effect of silicon(IV) phthalocyanines for colorectal cancer cells in photodynamic therapy by altering Wnt/13-catenin and apoptotic signaling

BARUT B., BARUT E. N., YALÇIN C. Ö., Ali Y. A., AKKAYA D., SEYHAN G., et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY , cilt.453, 2024 (SCI-Expanded, Scopus)

9. Synthesis and cholinesterases inhibitory effects of water soluble zinc(II) and silicon(IV) phthalocyanines bearing ({8-[3-(dimethylamino)phenoxy]octyl}oxy) groups

Usta B., Seyhan G., Akkaya D., Barut B., Bıyıklıoğlu Z., Özel A.

APPLIED ORGANOMETALLIC CHEMISTRY , sa.x, ss.1-10, 2024 (SCI-Expanded, Scopus)

10. Effective α-glycosidase inhibitors based on polyphenolic benzothiazole heterocycles

Sevimli E., SEYHAN G., AKKAYA D., SARI S., BARUT B., Koksoy B.

BIOORGANIC CHEMISTRY , cilt.147, 2024 (SCI-Expanded, Scopus)

11. In vitro and in silico investigation of FDA-approved drugs to be repurposed against Alzheimer's disease

Akkaya D., Seyhan G., Sari S., Barut B.

DRUG DEVELOPMENT RESEARCH , cilt.85, sa.3, 2024 (SCI-Expanded, Scopus)

12. Insights into the Biological Activity and Cytotoxic Mechanism of Epimedium pubigerum

SEYHAN G., AKKAYA D., KOLCİ K., REIS R., YAZICI BEKTAŞ N., BARUT E. N., et al.

CHEMISTRY & BIODIVERSITY , cilt.20, 2023 (SCI-Expanded, Scopus)

13. Synthesis and biological evaluation of novel zinc (II) and nickel (II) phthalocyanines as cholinesterase inhibitors

AKKAYA D., BARUT B., SARI S., REIS R., Fazli H., BIYIKLIOĞLU Z., et al.

JOURNAL OF ORGANOMETALLIC CHEMISTRY , cilt.995, 2023 (SCI-Expanded, Scopus)

14. Azole derivatives inhibit wildtype butyrylcholinesterase and its common mutants

SARI S., Onder S., AKKAYA D., SABUNCUOĞLU S., ZENGİN M., BARUT B., et al.

DRUG DEVELOPMENT RESEARCH , cilt.84, ss.1018-1028, 2023 (SCI-Expanded, Scopus)

15. Novel different furoic acid-linked axial silicon phthalocyanines: Design, syntheses, cholinesterases, tyrosinase inhibitory, and DNA damage studies

Yalazan H., AKKAYA D., Seyhan G., BARUT B., KANTEKİN H.

APPLIED ORGANOMETALLIC CHEMISTRY , cilt.37, sa.4, 2023 (SCI-Expanded, Scopus)

16. Evaluation of photodynamic therapy effects of novel zinc (II) phthalocyanine through a possible interaction with toll-like receptor signaling pathway

Barut B., Yalçın C. Ö., Altun Y., Akkaya D., Barut E. N., Baş H., et al.

APPLIED ORGANOMETALLIC CHEMISTRY , cilt.37, sa.4, 2023 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

17. Novel different furoic acid-linked axial silicon phthalocyanines: Design, syntheses, cholinesterases tyrosinase inhibitory, and DNA damage studies

Yalazan H., Akkaya D., Seyhan G., Barut B., Kantekin H.

APPLIED ORGANOMETALLIC CHEMISTRY , cilt.4, sa.37, ss.7040, 2023 (SCI-Expanded, Scopus)

18. Design, Synthesis, and Biological Evaluation of Some Benzothiazolone Derivatives as Cholinesterase Inhibitors

ALAGÖZ M. A., AKKAYA D., ARSLAN G., Uludağ B., ÖZDEMİR Z., BARUT B., et al.

ChemistrySelect , cilt.7, sa.46, 2022 (SCI-Expanded, Scopus)

19. Antifungal Azole Derivatives Featuring Naphthalene Prove Potent and Competitive Cholinesterase Inhibitors with Potential CNS Penetration According to the in Vitro and in Silico Studies

SARI S., AKKAYA D., ZENGİN M., SABUNCUOĞLU S., ÖZDEMİR Z., ALAGÖZ M. A., et al.

CHEMISTRY & BIODIVERSITY , cilt.19, sa.7, 2022 (SCI-Expanded, Scopus)

20. Quinoline-fused both non-peripheral and peripheral Zn-II and Mg-II phthalocyanines: Anti-cholinesterase, anti-alpha-glucosidase, DNA nuclease, antioxidant activities, and in silico studies

Yalazan H., TÜZÜN B., AKKAYA D., BARUT B., KANTEKİN H., YILDIRMIŞ S.

APPLIED ORGANOMETALLIC CHEMISTRY , cilt.36, sa.7, 2022 (SCI-Expanded, Scopus)

21. Synthesis and biological evaluation of peripherally tetra-({6-[3-(dimethylamino)phenoxy]hexyl}oxy) substituted water-soluble phthalocyanines as cholinesterases inhibitors

BIYIKLIOĞLU Z., Bas H., AKKAYA D., BARUT B.

APPLIED ORGANOMETALLIC CHEMISTRY , sa.4, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

22. Synthesis and in vitro α-glucosidase and cholinesterases inhibitory actions of water-soluble metallophthalocyanines bearing ({6-[3-(diethylamino)phenoxy]hexyl}oxy groups

KELEŞ T., BIYIKLIOĞLU Z., AKKAYA D., ÖZEL A., BARUT B.

Turkish Journal of Chemistry , cilt.46, sa.3, ss.786-795, 2022 (SCI-Expanded, Scopus, TRDizin)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 16

1. Suda Çözünebilen Zn(II) ve Co(II) Ftalosiyaninlerin Sentezi Ve Çok Hedefli Kolinesteraz ve Α-Glukozidaz İnhibitörü Olarak İncelenmesi

Bıyıklıoğlu Z., Keleş T., Özel A., Akkaya D., Aksel A. B.

37. Ulusal Kimya Kongresi, Erzurum, Türkiye, 24 - 27 Haziran 2026, ss.265-266, (Özet Bildiri)

2. EVALUATION OF TYROSINASE ACTIVITY OF NEW CHALCONE DERIVATIVES

Pehlivanlar Yavrucu E., Akkaya D., Şimşek R., Özel A.

VII.ULUSAL FARMASÖTİK KİMYA KONGRESİ, İzmir, Türkiye, 26 - 28 Ekim 2024, ss.40, (Özet Bildiri)

3. The Radical Scavenging and Cyclooxygenases Inhibitory Effects of Alchemilla Daghestanica Juz

Ortahisar M., Akkaya D., Seyhan G., Barut B., Yazıcı Bektaş N.

14th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Türkiye, 25 - 28 Haziran 2024, ss.376, (Özet Bildiri)

4. In Vitro Photodynamic Therapy Effects of Silicon (Iv) Phthalocyanine on Colorectal Cancer Cells

Akkaya D., Barut B., Barut E. N., Engin S., Yalçın C. Ö.

14th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Türkiye, 25 - 28 Haziran 2024, (Yayınlanmadı)

5. In vitro photodynaic therapy effecs of silicon (IV) phthalocyanine on colorectal cancer cells

AKKAYA D., BARUT B., BARUT E. N., ENGİN S., YALÇIN C. Ö.

14. International Symposium on Pharmaceutical Sciences, Türkiye, 25 - 28 Haziran 2024, (Özet Bildiri)

6. Synthesis and Biological Activity Studies on Novel Thiourea Derivatives

Türk S., Akkaya D., Kırılmaz B., Önal E. M., Barut B.

14th International Symposium on Pharmaceutical Sciences-ISOPS 2024, Ankara, Türkiye, 25 - 28 Haziran 2024, (Özet Bildiri)

7. Evaluation of cholinesterases inhibitory effects of some azole derivatives

Akkaya D., Barut B., Sarı S., Özel A.

6th International Eurasian Conference on Biological and Chemical Sciences, 11 - 13 Ekim 2023, ss.53, (Özet Bildiri)

8. Biological Activity Studies on Alchemilla pseudocartalinica Juz.

Uzunkaya Ç., Gökkaya İ., Akkaya D., Barut B., Renda G.

PSE Meeting 2023, Antalya, Türkiye, 12 - 15 Ekim 2023, ss.105, (Özet Bildiri)

9. In vitro investigation of biological activities of Epimedium pubigerum (DC.) Moren & Decne

Seyhan G., Akkaya D., Reis R., Kolci K., Yazıcı Bektaş N., Barut E. N., et al.

International Multidisciplinary Symposium on Drug Research and Development - DRD 2023, İzmir, Türkiye, 4 - 06 Mayıs 2023, ss.271, (Özet Bildiri)

10. Anticholinesterase properties of novel phthalocyanines

Akkaya D., Reis R., Sarı S., Bıyıklıoğlu Z., Özel A., Barut B.

International Multidisciplinary Symposium on Drug Research and Development - DRD 2023, İzmir, Türkiye, 4 - 06 Mayıs 2023, ss.270, (Özet Bildiri)

11. Comparison of Antioxidant Activities of Rosmarinus officinalis L. Extracts and Commercial Products

Ersoy S., Akkaya D., Gökkaya I., Barut B., Renda G.

The 9th International Mediterranean Symposium on Medicinal and Aromatic Plants, Ankara, Türkiye, 3 - 05 Mayıs 2023, ss.96, (Özet Bildiri)

12. Role of toll-lie receptors in photodynamic therapy of novel Zn(II) phthalocyanine compound on lung cancer cells

BARUT B., ALTUN ALI Y., AKKAYA D., BARUT E. N., BAŞ H., YALÇIN C. Ö., et al.

TBS International Biochemistry Congress 2022 - 33. National Biochemistry Congress, Türkiye, 26 - 30 Ekim 2022, (Özet Bildiri)

13. Role of toll-like receptors in photodynamic therapy of novel Zn(II) phtalocyanine compound on lung cancer cells

Barut B., Altun Y., Akkaya D., Barut E. N., Baş H., Yalçın C. Ö., et al.

International Biochemistry Congress // 33rd National Biochemistry Congress, İzmir, Türkiye, 26 - 30 Ekim 2022, ss.137, (Özet Bildiri)

14. Role of Toll-Like Receptors in Photodynamic Therapy of Novel Zn(II) Phtalocyanine Compound On Lung Cancer Cells

Barut B., Altun Ali Y., Akkaya D., Barut E. N., Baş H., Yalçın C. Ö., et al.

International Biochemistry Congress 2022, İzmir, Türkiye, 26 - 30 Ekim 2022, ss.44, (Özet Bildiri)

15. In Vitro and in silico investigations for the anticholinesterase effects of some imidazole derivatives

Akkaya D., Barut B., Sarı S., Sabuncuoğlu S.

TBS International Biochemistry Congress 2021-32nd National Biochemistry Congress, Gaziantep, Türkiye, 27 - 30 Ekim 2021, ss.113, (Özet Bildiri)

16. Kinolin grubu içeren periferal ve non-periferal çinko ve magnezyum ftalosiyanin bileşiklerinin sentezi, asetilkolinesteraz (AChE), butirilkolinesteraz (BuChE) ve glukozidaz enzimleri üzerindeki inhibitör etkileri

Yalazan H., Akkaya D., Barut B., Yıldırmış S., Kantekin H.

33. Ulusal Kimya Kongresi, Tekirdağ, Türkiye, 7 - 09 Ekim 2021, ss.23, (Özet Bildiri)

Kitaplar 1

1. Aminoasitler ve Beyin

BARUT B., AKKAYA D.

BEYİN BİYOKİMYASI, Fatih KAR, Ceyhan HACIOĞLU, Editör, NOBEL AKADEMİK YAYINCILIK, ss.31-53, 2023

Metrikler

Yayın

Yayın (WoS)

Yayın (Scopus)

Atıf (WoS)

115

H-İndeks (WoS)

Atıf (Scopus)

120

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks (Scholar)

Atıf (TrDizin)

H-İndeks (TrDizin)

Atıf (Diğer Toplam)

Proje

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

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