Prof. CAN ÖZGÜR YALÇIN

1. In vitro photodynamic therapy evaluation of novel silicon(IV) phthalocyanines against endometrial cancer

Ali Y., SEYHAN G., Koksoy B., KELEŞ T., YALÇIN C. Ö., Amin M. M., et al.

JOURNAL OF MOLECULAR STRUCTURE , vol.1373, 2026 (SCI-Expanded, Scopus)

2. Design and biological evaluation of a quinoline-substituted silicon phthalocyanines for photodynamic therapy of endometrial cancer: topoisomerase IIα targeting and apoptosis induction

Seyhan G., Ali Y., Barut E. N., Amin M. M., Keles T., Sari S., et al.

INORGANIC CHEMISTRY COMMUNICATIONS , vol.190, 2026 (SCI-Expanded, Scopus)

3. Methoxychalcones: a promising therapeutic agent for obesity management

Erik Z., Erik İ., Şener S. Ö., Yalçın C. Ö., Kutlu A., Yenilmez E., et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , vol.821, no.2026, pp.1-8, 2026 (SCI-Expanded, Scopus)

4. Copper-based nanoparticles-associated neurotoxicity: ions or particles?

Keskin Z., Yalçın C. Ö., Yenilmez E., Öztaş E., Abudayyak M.

TOXICOLOGY MECHANISMS AND METHODS , vol.36, no.5, pp.1-17, 2026 (SCI-Expanded, Scopus)

5. Toxicological Evaluation of Siloxanes by In Silico Approaches

YILMAZ SARIALTIN S., YALÇIN C. Ö.

ISTANBUL JOURNAL OF PHARMACY , vol.55, no.2, pp.233-244, 2025 (ESCI, TRDizin)

6. Evaluation of the genotoxicity/mutagenicity of levetiracetam, lamotrigine, and oxcarbazepine using in silico methods

YILMAZ SARIALTIN S., YALÇIN C. Ö.

Journal of Research in Pharmacy , vol.29, no.4, pp.1682-1692, 2025 (ESCI, Scopus, TRDizin)

7. Evaluation of synthesized methoxy chalcones for therapeutic potential through in vitro and in silico methods

Erik Z., ERİK İ., YALÇIN C. Ö., ŞENER S. Ö., ALPAY KARAOĞLU Ş., TATAR YILMAZ G., et al.

Journal of Research in Pharmacy , vol.29, no.4, pp.1693-1711, 2025 (ESCI, Scopus, TRDizin)

8. Synthesis, characterization, in vitro cholinesterase inhibition and cytotoxic activity of silicon(IV) phthalocyanines containing anthraquinone groups against lung and colorectal cancer cells

Keleş T., Bıyıklıoğlu Z., Ali Y. A., Akkaya D., Yalçın C. Ö., Barut B.

JOURNAL OF MOLECULAR STRUCTURE , vol.1330, 2025 (SCI-Expanded, Scopus) Sustainable Development

9. Assessing Toxicological Safety of EverX Posterior and Filtek Ultimate: An In-Depth Extractable and Leachable Study Under ISO 10993-17 and 10993-18 Standards

AYDINOĞLU A., ERDEM HEPŞENOĞLU Y., YALÇIN C. Ö., Saǧır K., Ölçer Us Y., Eroǧlu Ş. E., et al.

ACS Omega , vol.10, no.10, pp.9903-9918, 2025 (SCI-Expanded, Scopus)

10. Comprehensive evaluation of the toxicological effects of commonly encountered synthetic cathinones using in silico methods

YALÇIN C. Ö., YILMAZ SARIALTIN S., Raitano G., Benfenati E.

TOXICOLOGY RESEARCH , vol.14, no.1, 2025 (SCI-Expanded, Scopus) Sustainable Development

11. The synthesis and therapeutic effect of silicon(IV) phthalocyanines for colorectal cancer cells in photodynamic therapy by altering Wnt/13-catenin and apoptotic signaling

BARUT B., BARUT E. N., YALÇIN C. Ö., Ali Y. A., AKKAYA D., SEYHAN G., et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY , vol.453, 2024 (SCI-Expanded, Scopus)

12. In vitro cholinesterases, tyrosinase, α-glucosidase inhibitory and anticancer effects of novel silicon phthalocyanines containing geraniol/phytol

Yalazan H., BARUT B., YALÇIN C. Ö., KANTEKİN H., YILDIRMIŞ S.

INORGANIC CHEMISTRY COMMUNICATIONS , vol.165, 2024 (SCI-Expanded, Scopus)

13. Highly water soluble axial disubstituted silicon(IV) phthalocyanine, naphthalocyanine: Synthesis, DNA interaction and anticancer effects against human lung (A549), liver (SNU-398), melanoma (SK-MEL128), prostate (DU-145), breast (BT-20) cell lines

Baş H., Bıyıklıoğlu Z., Barut B., Yalçın C. Ö., Özel A.

INORGANIC CHEMISTRY COMMUNICATIONS , vol.156, 2023 (SCI-Expanded, Scopus) Sustainable Development

14. Design, Synthesis, Biological Activity and Molecular Docking Studies of New Imine-Chalcone Derivatives

Çelik G., Yılmaz G. T., BARUT B., YALÇIN C. Ö., YAYLI N.

PHARMACEUTICAL CHEMISTRY JOURNAL , vol.57, no.4, pp.550-558, 2023 (SCI-Expanded, Scopus)

15. Evaluation of photodynamic therapy effects of novel zinc (II) phthalocyanine through a possible interaction with toll-like receptor signaling pathway

Barut B., Yalçın C. Ö., Altun Y., Akkaya D., Barut E. N., Baş H., et al.

APPLIED ORGANOMETALLIC CHEMISTRY , vol.37, no.4, 2023 (SCI-Expanded, Scopus) Sustainable Development

16. DNA interaction, cytotoxic and phototoxic properties of new water-soluble zinc (II) phthalocyanines

BIYIKLIOĞLU Z., Bas H., ALTUN ALİ Y., YALÇIN C. Ö., BARUT B.

APPLIED ORGANOMETALLIC CHEMISTRY , no.12, 2022 (SCI-Expanded, Scopus) Sustainable Development

17. Axially disubstituted silicon (IV) phthalocyanines containing different isoxazolyl groups: Design, syntheses, binding and in vitro phototoxic activities against SH-SY5Y cells

Yalazan H., BARUT B., YILDIRIM S., YALÇIN C. Ö., KANTEKİN H.

Journal of Molecular Structure , vol.1262, 2022 (SCI-Expanded, Scopus)

18. Synthesis of water-soluble BODIPY dyes and investigation of their DNA interaction properties and cytotoxicity/phototoxicity

KELEŞ T., BARUT B., YILDIRIM S., YALÇIN C. Ö., BIYIKLIOĞLU Z.

APPLIED ORGANOMETALLIC CHEMISTRY , vol.35, no.11, 2021 (SCI-Expanded, Scopus)

19. Peripheral or nonperipheral tetra-[4-(9H-carbazol-9-yl)phenoxy] substituted cobalt(II), manganese(III) phthalocyanines: Synthesis, acetylcholinesterase, butyrylcholinesterase, and α-glucosidase inhibitory effects and anticancer activities

Barut B., Keles T., BIYIKLIOĞLU Z., YALÇIN C. Ö.

Applied Organometallic Chemistry , vol.35, no.1, 2021 (SCI-Expanded, Scopus) Sustainable Development

20. The water soluble Zn(II) and Mg(II) phthalocyanines: Synthesis, photochemical, DNA photodamage and PDT effects against A549 cells

Barut B., YALÇIN C. Ö., DEMİRBAŞ Ü.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY , vol.405, 2021 (SCI-Expanded, Scopus)

21. Photodynamic therapy effect of morpholinium containing silicon (IV) phthalocyanine on HCT-116 cells.

YALÇIN C. Ö., Barut B., BARUT E. N., DEMİRBAŞ Ü., DİNÇER T., ENGİN S., et al.

Photodiagnosis and photodynamic therapy , vol.32, pp.101975, 2020 (SCI-Expanded, Scopus)

22. Development and in vitro evaluation of BSA-coated liposomes containing Zn (II) phthalocyanine-containing ferrocene groups for photodynamic therapy of lung cancer

ÇOBAN Ö., Barut B., YALÇIN C. Ö., ÖZEL A., BIYIKLIOĞLU Z.

Journal of Organometallic Chemistry , vol.925, 2020 (SCI-Expanded, Scopus) Sustainable Development

23. The novel Zn(II) phthalocyanines: Synthesis, characterization, photochemical, DNA interaction and cytotoxic/phototoxic properties

Barut B., YALÇIN C. Ö., DEMİRBAŞ Ü., AKÇAY H. T., KANTEKİN H., ÖZEL A.

JOURNAL OF MOLECULAR STRUCTURE , vol.1218, 2020 (SCI-Expanded, Scopus)

24. Effects of boric acid on cell death and oxidative stress of mouse TM3 Leydig cells in vitro

YALÇIN C. Ö., Abudayyak M.

Journal of Trace Elements in Medicine and Biology , vol.61, 2020 (SCI-Expanded, Scopus)

25. Photochemical and in vitro phototoxic properties of Zn (II) phthalocyanine bearing piperidinium groups on different cell lines

Barut B., YALÇIN C. Ö., DEMİRBAŞ Ü., ÖZEL A.

JOURNAL OF ORGANOMETALLIC CHEMISTRY , vol.921, 2020 (SCI-Expanded, Scopus) Sustainable Development

26. Evaluation of oxidative stress and immune parameters of boron exposed males and females

Başaran N., Duydu Y., Bacanlı M., Gül Anlar H., DİLSİZ S. A., Üstündağ A., et al.

Food and Chemical Toxicology , vol.142, 2020 (SCI-Expanded, Scopus)

27. Quantification of phenolic and flavonoid contents and some biological activities of Ornithogalum sigmoideum Freyn Sint

YALÇIN C. Ö., YILMAZ SARIALTIN S., ÇİÇEK POLAT D.

JOURNAL OF RESEARCH IN PHARMACY , vol.24, no.4, pp.487-496, 2020 (ESCI, Scopus, TRDizin)

28. Evaluation of Cytotoxic Effects of 2-Monochloropropanediol (2-MCPD) on Mouse TM3 Leydig and TM4 Sertoli Cells in vitro

YALÇIN C. Ö., YILMAZ SARIALTIN S., ABUDAYYAK M., YENİLMEZ E.

Journal of Nutrition and Dietetics , vol.48, no.1, pp.55-62, 2020 (TRDizin)

29. Occupational exposure of dental technicians to methyl methacrylate: Genotoxicity assessment

Soykut B., Erdem O., YALÇIN C. Ö., ÜSTÜNDAĞ A., DUYDU Y., Akay C., et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS , vol.852, 2020 (SCI-Expanded, Scopus)

30. Synthesis of axially disubstituted quaternized silicon phthalocyanines as a promising photosensitizer for the photodynamic treatment of HCT-116, A549 and SH-SY5Y cancer cell lines

YALÇIN C. Ö., Bas H., Barut B., ÖZEL A., BIYIKLIOĞLU Z.

DALTON TRANSACTIONS , no.15, pp.4927-4934, 2020 (SCI-Expanded, Scopus) Sustainable Development

31. **Synthesis, DNA interaction, in vitro/in silico topoisomerase II inhibition and photodynamic therapy activities of two cationic BODIPY derivatives**

Barut B., COBAN O., YALÇIN C. Ö., Bas H., SARI S., Biyiklioglu Z., et al.

DYES AND PIGMENTS , 2020 (SCI-Expanded, Scopus) Sustainable Development

32. DNA interaction and anticancer properties of new peripheral phthalocyanines carrying tosylated 4-morpholinoaniline units

Yalazan H., Barut B., Ertem B., Yalçın C. Ö., Ünver Y., Özel A., et al.

POLYHEDRON , vol.177, 2020 (SCI-Expanded, Scopus) Sustainable Development

33. Non-aggregated axially disubstituted silicon phthalocyanines: Synthesis, DNA cleavage and in vitro cytotoxic/phototoxic anticancer activities against SH-SY5Y cell line

Barut B., Biyikhoglu Z., YALÇIN C. Ö., Abudayyak M.

DYES AND PIGMENTS , vol.172, 2020 (SCI-Expanded, Scopus)

34. Novel water soluble BODIPY compounds: Synthesis, photochemical, DNA interaction, topoisomerases inhibition and photodynamic activity properties

Barut B., YALÇIN C. Ö., SARI S., ÇOBAN Ö., Keles T., BIYIKLIOĞLU Z., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , vol.183, 2019 (SCI-Expanded, Scopus) Sustainable Development

35. Evaluation of the DNA damage in lymphocytes, sperm and buccal cells of workers under environmental and occupational boron exposure conditions.

BAŞARAN N., DUYDU Y., ÜSTÜNDAĞ A., TANER G., AYDıN S., ANLAR H., et al.

Mutation research , vol.843, pp.33-39, 2019 (SCI-Expanded, Scopus)

36. Environmental boron exposure does not induce DNA damage in lymphocytes and buccal cells of females: DNA damage in lymphocytes and buccal cells of boron exposed females.

BAŞARAN N., DUYDU Y., ÜSTÜNDAĞ A., TANER G., Aydin D., ANLAR H., et al.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) , vol.53, pp.150-153, 2019 (SCI-Expanded, Scopus)

37. Boron-exposed male workers in Turkey: no change in sperm Y:X chromosome ratio and in offspring’s sex ratio

Duydu Y., Başaran N., Yalçın C. Ö., Üstündağ A., Aydın S., Anlar H. G., et al.

Archives of Toxicology , vol.93, no.3, pp.743-751, 2019 (SCI-Expanded, Scopus)

38. Is there an association between extreme levels of boron exposure and decrease in Y:X sperm ratio in men? results of an epidemiological study Erkeklerde Y:X sperm oranındaki azalma ile aşırı düzeyde bor maruziyeti arasında bir ilişki var mıdır? epidemiyolojik çalışma sonuçları

Yalcin C. Ö., Ustundag A., Duydu Y.

Turkish Journal of Pharmaceutical Sciences , vol.16, no.1, pp.96-100, 2019 (ESCI, Scopus, TRDizin) Sustainable Development

39. Synthesis & anticancer evaluation of new substituted 2-(3,4- Dimethoxyphenyl)benzazoles

Karaaslan C., Duydu Y., Ustundag A., Yalcin C. Ö., Kaskatepe B., Goker H.

Medicinal Chemistry , vol.15, no.3, pp.287-297, 2019 (SCI-Expanded, Scopus)

40. Evaluation of FSH, LH, testosterone levels and semen parameters in male boron workers under extreme exposure conditions

Duydu Y., Başaran N., Aydın S., Üstündağ A., Yalçın C. Ö., Anlar H. G., et al.

Archives of Toxicology , vol.92, no.10, pp.3051-3059, 2018 (SCI-Expanded, Scopus)

41. Birth weights of newborns and pregnancy outcomes of environmentally boron-exposed females in Turkey

Duydu Y., Başaran N., Üstündağ A., Aydın S., Yalçın C. Ö., Anlar H. G., et al.

Archives of Toxicology , vol.92, no.8, pp.2475-2485, 2018 (SCI-Expanded, Scopus)

42. Evaluation of the radioprotective effect of Turkish propolis on foreskin fibroblast cells

Yalcin C. Ö., ALİYAZICIOĞLU Y., DEMİR S., Turan I., BAHAT Z., Mısır S., et al.

Journal of Cancer Research and Therapeutics , vol.12, no.2, pp.990-994, 2016 (SCI-Expanded, Scopus)

43. Synthesis and In Vitro Activity of Polyhalogenated 2-phenylbenzimidazoles as a New Class of anti-MRSA and Anti-VRE Agents.

GÖKER H., KARAASLAN C., PÜSKÜLLÜ M., YILDIZ S., DUYDU Y., ÜSTÜNDAĞ A., et al.

Chemical biology & drug design , vol.87, pp.57-68, 2016 (SCI-Expanded, Scopus)

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