Metrikler
Yayın
72
Açık Erişim
1
BM Sürdürülebilir Kalkınma Amaçları
Eğitim Bilgileri
2012 - 2017
2012 - 2017Doktora
Ankara Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Toksikoloji Anabilim Dalı, Türkiye
2009 - 2012
2009 - 2012Yüksek Lisans
Karadeniz Teknik Üniversitesi, Sağlık Bilimleri Enstitüsü, Tıbbi Biyokimya Anabilim Dalı, Türkiye
2002 - 2006
2002 - 2006Lisans
Atatürk Üniversitesi, Eczacılık Fakültesi, Eczacılık, Türkiye
Yaptığı Tezler
2017
2017Doktora
Bor maruziyetinin insanların üreme fonksiyonu üzerindeki toksik etkilerinin araştırılması
Ankara Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Toksikoloji
2012
2012Yüksek Lisans
Türk propolis ekstraktlarının iyonizan (Gama) radyasyonla uyarılmış insan lenfositleri üzerine olası radyoprotektif etkisinin değerlendirilmesi
Karadeniz Teknik Üniversitesi, Sağlık Bilimleri Fakültesi, Tıbbi Biyokimya
Yabancı Diller
B2 Orta Üstü
B2 Orta Üstüİngilizce
Araştırma Alanları
Sağlık Bilimleri
Eczacılık
Meslek Bilimleri
Farmasötik Toksikoloji
Akademik Ünvanlar / Görevler
2021 - Devam Ediyor
2021 - Devam EdiyorDoç. Dr.
Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2018 - 2021
2018 - 2021Dr. Öğr. Üyesi
Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2017 - 2018
2017 - 2018Yrd. Doç. Dr.
Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2012 - 2016
2012 - 2016Araştırma Görevlisi
Ankara Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Yönetimsel Görevler
2019 - Devam Ediyor
2019 - Devam EdiyorAnabilim/Bilim Dalı Başkanı
Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2019 - 2022
2019 - 2022Fakülte Yönetim Kurulu Üyesi
Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Eczacılık
Akademi Dışı Deneyim
2007 - 2012
2007 - 2012Eczacı
Kamu Hastanesi, Sağlık Bakanlığı, Eczacı, Eczacı
Makaleler
Tümü (38)
SCI-E, SSCI, AHCI (33)
SCI-E, SSCI, AHCI, ESCI (37)
ESCI (4)
Scopus (36)
TRDizin (5)
2025
20251. Toxicological Evaluation of Siloxanes by In Silico Approaches
YILMAZ SARIALTIN S., YALÇIN C. Ö.
ISTANBUL JOURNAL OF PHARMACY
, cilt.55, sa.2, ss.233-244, 2025 (ESCI, TRDizin)
2025
20252. Evaluation of the genotoxicity/mutagenicity of levetiracetam, lamotrigine, and oxcarbazepine using in silico methods
YILMAZ SARIALTIN S., YALÇIN C. Ö.
Journal of Research in Pharmacy
, cilt.29, sa.4, ss.1682-1692, 2025 (ESCI, Scopus, TRDizin)
2025
20253. Synthesis, characterization, in vitro cholinesterase inhibition and cytotoxic activity of silicon(IV) phthalocyanines containing anthraquinone groups against lung and colorectal cancer cells
KELEŞ T., BIYIKLIOĞLU Z., Ali Y. A., AKKAYA D., YALÇIN C. Ö., BARUT B.
Journal of Molecular Structure
, cilt.1330, 2025 (SCI-Expanded, Scopus)
2025
20254. Evaluation of synthesized methoxy chalcones for therapeutic potential through in vitro and in silico methods
Erik Z., ERİK İ., YALÇIN C. Ö., ŞENER S. Ö., ALPAY KARAOĞLU Ş., TATAR YILMAZ G., et al.
Journal of Research in Pharmacy
, cilt.29, sa.4, ss.1693-1711, 2025 (ESCI, Scopus, TRDizin)
2025
20255. Assessing Toxicological Safety of EverX Posterior and Filtek Ultimate: An In-Depth Extractable and Leachable Study Under ISO 10993-17 and 10993-18 Standards
AYDINOĞLU A., ERDEM HEPŞENOĞLU Y., YALÇIN C. Ö., Saǧır K., Ölçer Us Y., Eroǧlu Ş. E., et al.
ACS Omega
, cilt.10, sa.10, ss.9903-9918, 2025 (SCI-Expanded, Scopus)
2025
20256. Comprehensive evaluation of the toxicological effects of commonly encountered synthetic cathinones using in silico methods
YALÇIN C. Ö., YILMAZ SARIALTIN S., Raitano G., Benfenati E.
TOXICOLOGY RESEARCH
, sa.1, 2025 (SCI-Expanded, Scopus)
2024
20247. The synthesis and therapeutic effect of silicon(IV) phthalocyanines for colorectal cancer cells in photodynamic therapy by altering Wnt/13-catenin and apoptotic signaling
BARUT B., BARUT E. N., YALÇIN C. Ö., Ali Y. A., AKKAYA D., SEYHAN G., et al.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
, cilt.453, 2024 (SCI-Expanded, Scopus)
2024
20248. In vitro cholinesterases, tyrosinase, α-glucosidase inhibitory and anticancer effects of novel silicon phthalocyanines containing geraniol/phytol
Yalazan H., BARUT B., YALÇIN C. Ö., KANTEKİN H., YILDIRMIŞ S.
INORGANIC CHEMISTRY COMMUNICATIONS
, cilt.165, 2024 (SCI-Expanded, Scopus)
2023
20239. Highly water soluble axial disubstituted silicon(IV) phthalocyanine, naphthalocyanine: Synthesis, DNA interaction and anticancer effects against human lung (A549), liver (SNU-398), melanoma (SK-MEL128), prostate (DU-145), breast (BT-20) cell lines
Baş H., Bıyıklıoğlu Z., Barut B., Yalçın C. Ö., Özel A.
INORGANIC CHEMISTRY COMMUNICATIONS
, cilt.156, 2023 (SCI-Expanded, Scopus)
2023
202310. Design, Synthesis, Biological Activity and Molecular Docking Studies of New Imine-Chalcone Derivatives
Çelik G., Yılmaz G. T., BARUT B., YALÇIN C. Ö., YAYLI N.
PHARMACEUTICAL CHEMISTRY JOURNAL
, cilt.57, sa.4, ss.550-558, 2023 (SCI-Expanded, Scopus)
2023
202311. Evaluation of photodynamic therapy effects of novel zinc (II) phthalocyanine through a possible interaction with toll-like receptor signaling pathway
Barut B., Yalçın C. Ö., Altun Y., Akkaya D., Barut E. N., Baş H., et al.
APPLIED ORGANOMETALLIC CHEMISTRY
, cilt.37, sa.4, 2023 (SCI-Expanded, Scopus)
2022
202212. DNA interaction, cytotoxic and phototoxic properties of new water-soluble zinc (II) phthalocyanines
BIYIKLIOĞLU Z., Bas H., ALTUN ALİ Y., YALÇIN C. Ö., BARUT B.
APPLIED ORGANOMETALLIC CHEMISTRY
, sa.12, 2022 (SCI-Expanded, Scopus)
2022
202213. Axially disubstituted silicon (IV) phthalocyanines containing different isoxazolyl groups: Design, syntheses, binding and in vitro phototoxic activities against SH-SY5Y cells
Yalazan H., BARUT B., YILDIRIM S., YALÇIN C. Ö., KANTEKİN H.
Journal of Molecular Structure
, cilt.1262, 2022 (SCI-Expanded, Scopus)
2021
202114. Synthesis of water-soluble BODIPY dyes and investigation of their DNA interaction properties and cytotoxicity/phototoxicity
KELEŞ T., BARUT B., YILDIRIM S., YALÇIN C. Ö., BIYIKLIOĞLU Z.
APPLIED ORGANOMETALLIC CHEMISTRY
, cilt.35, sa.11, 2021 (SCI-Expanded, Scopus)
2021
202115. The water soluble Zn(II) and Mg(II) phthalocyanines: Synthesis, photochemical, DNA photodamage and PDT effects against A549 cells
Barut B., YALÇIN C. Ö., DEMİRBAŞ Ü.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
, cilt.405, 2021 (SCI-Expanded, Scopus)
2021
202116. Peripheral or nonperipheral tetra-[4-(9H-carbazol-9-yl)phenoxy] substituted cobalt(II), manganese(III) phthalocyanines: Synthesis, acetylcholinesterase, butyrylcholinesterase, and α-glucosidase inhibitory effects and anticancer activities
Barut B., Keles T., BIYIKLIOĞLU Z., YALÇIN C. Ö.
Applied Organometallic Chemistry
, cilt.35, sa.1, 2021 (SCI-Expanded, Scopus)
2020
202017. Photodynamic therapy effect of morpholinium containing silicon (IV) phthalocyanine on HCT-116 cells.
YALÇIN C. Ö., Barut B., BARUT E. N., DEMİRBAŞ Ü., DİNÇER T., ENGİN S., et al.
Photodiagnosis and photodynamic therapy
, cilt.32, ss.101975, 2020 (SCI-Expanded, Scopus)
2020
202018. Development and in vitro evaluation of BSA-coated liposomes containing Zn (II) phthalocyanine-containing ferrocene groups for photodynamic therapy of lung cancer
ÇOBAN Ö., Barut B., YALÇIN C. Ö., ÖZEL A., BIYIKLIOĞLU Z.
Journal of Organometallic Chemistry
, cilt.925, 2020 (SCI-Expanded, Scopus)
2020
202019. The novel Zn(II) phthalocyanines: Synthesis, characterization, photochemical, DNA interaction and cytotoxic/phototoxic properties
Barut B., YALÇIN C. Ö., DEMİRBAŞ Ü., AKÇAY H. T., KANTEKİN H., ÖZEL A.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1218, 2020 (SCI-Expanded, Scopus)
2020
202020. Effects of boric acid on cell death and oxidative stress of mouse TM3 Leydig cells in vitro
YALÇIN C. Ö., Abudayyak M.
Journal of Trace Elements in Medicine and Biology
, cilt.61, 2020 (SCI-Expanded, Scopus)
2020
202021. Evaluation of oxidative stress and immune parameters of boron exposed males and females
Başaran N., Duydu Y., Bacanlı M., Gül Anlar H., DİLSİZ S. A., Üstündağ A., et al.
Food and Chemical Toxicology
, cilt.142, 2020 (SCI-Expanded, Scopus)
2020
202022. Photochemical and in vitro phototoxic properties of Zn (II) phthalocyanine bearing piperidinium groups on different cell lines
Barut B., YALÇIN C. Ö., DEMİRBAŞ Ü., ÖZEL A.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
, cilt.921, 2020 (SCI-Expanded, Scopus)
2020
202023. Evaluation of Cytotoxic Effects of 2-Monochloropropanediol (2-MCPD) on Mouse TM3 Leydig and TM4 Sertoli Cells in vitro
YALÇIN C. Ö., YILMAZ SARIALTIN S., ABUDAYYAK M., YENİLMEZ E.
Journal of Nutrition and Dietetics , cilt.48, sa.1, ss.55-62, 2020 (TRDizin)
2020
202024. Synthesis of axially disubstituted quaternized silicon phthalocyanines as a promising photosensitizer for the photodynamic treatment of HCT-116, A549 and SH-SY5Y cancer cell lines
YALÇIN C. Ö., Bas H., Barut B., ÖZEL A., BIYIKLIOĞLU Z.
DALTON TRANSACTIONS
, sa.15, ss.4927-4934, 2020 (SCI-Expanded, Scopus)
2020
202025. Occupational exposure of dental technicians to methyl methacrylate: Genotoxicity assessment
Soykut B., Erdem O., YALÇIN C. Ö., ÜSTÜNDAĞ A., DUYDU Y., Akay C., et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
, cilt.852, 2020 (SCI-Expanded, Scopus)
2020
202026. Synthesis, DNA interaction, in vitro/in silico topoisomerase II inhibition and photodynamic therapy activities of two cationic BODIPY derivatives
Barut B., COBAN O., YALÇIN C. Ö., Bas H., SARI S., Biyiklioglu Z., et al.
DYES AND PIGMENTS
, 2020 (SCI-Expanded, Scopus)
2020
202027. DNA interaction and anticancer properties of new peripheral phthalocyanines carrying tosylated 4-morpholinoaniline units
Yalazan H., Barut B., Ertem B., Yalçın C. Ö., Ünver Y., Özel A., et al.
POLYHEDRON
, cilt.177, 2020 (SCI-Expanded, Scopus)
2020
202028. Non-aggregated axially disubstituted silicon phthalocyanines: Synthesis, DNA cleavage and in vitro cytotoxic/phototoxic anticancer activities against SH-SY5Y cell line
Barut B., Biyikhoglu Z., YALÇIN C. Ö., Abudayyak M.
DYES AND PIGMENTS
, cilt.172, 2020 (SCI-Expanded, Scopus)
2019
201929. Novel water soluble BODIPY compounds: Synthesis, photochemical, DNA interaction, topoisomerases inhibition and photodynamic activity properties
Barut B., YALÇIN C. Ö., SARI S., ÇOBAN Ö., Keles T., BIYIKLIOĞLU Z., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.183, 2019 (SCI-Expanded, Scopus)
2019
201930. Evaluation of the DNA damage in lymphocytes, sperm and buccal cells of workers under environmental and occupational boron exposure conditions.
BAŞARAN N., DUYDU Y., ÜSTÜNDAĞ A., TANER G., AYDıN S., ANLAR H., et al.
Mutation research
, cilt.843, ss.33-39, 2019 (SCI-Expanded, Scopus)
2019
201931. Environmental boron exposure does not induce DNA damage in lymphocytes and buccal cells of females: DNA damage in lymphocytes and buccal cells of boron exposed females.
BAŞARAN N., DUYDU Y., ÜSTÜNDAĞ A., TANER G., Aydin D., ANLAR H., et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
, cilt.53, ss.150-153, 2019 (SCI-Expanded, Scopus)
2019
201932. Boron-exposed male workers in Turkey: no change in sperm Y:X chromosome ratio and in offspring’s sex ratio
Duydu Y., Başaran N., Yalçın C. Ö., Üstündağ A., Aydın S., Anlar H. G., et al.
Archives of Toxicology
, cilt.93, sa.3, ss.743-751, 2019 (SCI-Expanded, Scopus)
2019
201933. Is there an association between extreme levels of boron exposure and decrease in Y:X sperm ratio in men? results of an epidemiological study Erkeklerde Y:X sperm oranındaki azalma ile aşırı düzeyde bor maruziyeti arasında bir ilişki var mıdır? epidemiyolojik çalışma sonuçları
Yalcin C. Ö., Ustundag A., Duydu Y.
Turkish Journal of Pharmaceutical Sciences
, cilt.16, sa.1, ss.96-100, 2019 (ESCI, Scopus, TRDizin)
2019
201934. Synthesis & anticancer evaluation of new substituted 2-(3,4- Dimethoxyphenyl)benzazoles
Karaaslan C., Duydu Y., Ustundag A., Yalcin C. Ö., Kaskatepe B., Goker H.
Medicinal Chemistry
, cilt.15, sa.3, ss.287-297, 2019 (SCI-Expanded, Scopus)
2018
201835. Evaluation of FSH, LH, testosterone levels and semen parameters in male boron workers under extreme exposure conditions
Duydu Y., Başaran N., Aydın S., Üstündağ A., Yalçın C. Ö., Anlar H. G., et al.
Archives of Toxicology
, cilt.92, sa.10, ss.3051-3059, 2018 (SCI-Expanded, Scopus)
2018
201836. Birth weights of newborns and pregnancy outcomes of environmentally boron-exposed females in Turkey
Duydu Y., Başaran N., Üstündağ A., Aydın S., Yalçın C. Ö., Anlar H. G., et al.
Archives of Toxicology
, cilt.92, sa.8, ss.2475-2485, 2018 (SCI-Expanded, Scopus)
2016
201637. Evaluation of the radioprotective effect of Turkish propolis on foreskin fibroblast cells
Yalcin C. Ö., ALİYAZICIOĞLU Y., DEMİR S., Turan I., BAHAT Z., Mısır S., et al.
Journal of Cancer Research and Therapeutics
, cilt.12, sa.2, ss.990-994, 2016 (SCI-Expanded, Scopus)
2016
201638. Synthesis and In Vitro Activity of Polyhalogenated 2-phenylbenzimidazoles as a New Class of anti-MRSA and Anti-VRE Agents.
GÖKER H., KARAASLAN C., PÜSKÜLLÜ M., YILDIZ S., DUYDU Y., ÜSTÜNDAĞ A., et al.
Chemical biology & drug design
, cilt.87, ss.57-68, 2016 (SCI-Expanded, Scopus)